Imidazo[1,2-c][1,3]benzodiazepines

Details Imidazo[1,2-c][1,3]benzodiazepines Imidazo[1,2-c][1,3]benzodiazepines

1984-04-23

1985-03-26

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239BC, 2602433, 2602456, A61K 31415, C07D48704

Patent

active

045073112

ABSTRACT:
5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines, for example compounds of the formula ##STR1## in which e.g., R.sub.1, R.sub.2 and R.sub.4 are hydrogen, R.sub.3 is methyl and C.sub.n H.sub.2n is CH.sub.2 CH.sub.2, have neuroleptic and/or antihistaminic activity. The synthesis, pharmaceutical compositions and methods of treatment utilizing such compounds are described.

REFERENCES:
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patent: 4280957 (1981-07-01), Walser et al.
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patent: 4444688 (1984-04-01), Vlattas
Wright, Jr. et al., J. Med. Chem., 1980, 23, 462-465.

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