Imidazo[1,2-a]quinoline derivatives useful as anxiolytics

Details Imidazo[1,2-a]quinoline derivatives useful as anxiolytics Imidazo[1,2-a]quinoline derivatives useful as anxiolytics

1982-03-25

1983-06-07

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 84, 546153, 546174, 546 86, 546 87, 546 85, A61K 3147, C07D47114

Patent

active

043870988

ABSTRACT:
Novel imidazo[1,2-a]quinolines of the formula ##STR1## wherein R is selected from the group consisting of alkyl of 1 to 8 carbon atoms, thienyl, pyridyl and phenyl optionally substituted with at least one member of the group consisting of halogen, alkyl of 1 to 5 carbon atoms and alkoxy of 1 to 5 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, halogen, alkyl and alkoxy of 1 to 8 carbon atoms,s cyclohexyl, --NO.sub.2 and phenoxy, R.sub.3 is selected from the group consisting of alkoxy and alkylthio of 1 to 8 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a remarkable anxiolytic activity and a hypnotic activity and their preparation.

REFERENCES:
patent: 4279912 (1981-07-01), Ager et al.

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