Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac dis

Details Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac dis Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac dis

1998-12-30

2000-01-11

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142282, 5142332, 514253, 544 61, 544127, 544362, 546121, A61K 31435, C07D47104

Patent

active

060136545

ABSTRACT:
The present invention relates to imidazo[1,2-a]pyridine compounds of formula I which are dopamine D-4 antagonists and useful as anti-psychotic agents. ##STR1##

REFERENCES:
patent: 3362956 (1968-01-01), Archer
patent: 3381009 (1968-04-01), Palazzo et al.
patent: 3472854 (1969-10-01), Archer
patent: 3511841 (1970-05-01), Archer
patent: 3658822 (1972-04-01), Fauran et al.
patent: 4202977 (1980-05-01), Irikura et al.
patent: 4910199 (1990-03-01), Bourguignon et al.
patent: 4988698 (1991-01-01), Kato et al.
patent: 5434169 (1995-07-01), Jegham et al.
VanTol et al., Nature, vol.350, p. 610-614, 1991.
Derwent Abstracts 10911 K/05, for JP 57-20685 (Dec. 18, 1982).
Derwent Abstracts 34368B/18, for JP 54-39093 (Mar. 24, 1979).

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