Imidate derivatives of pharmaceutically useful anticonvulsant su

Details Imidate derivatives of pharmaceutically useful anticonvulsant su Imidate derivatives of pharmaceutically useful anticonvulsant su

1992-06-11

1993-11-02

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549387, 549338, 549 31, A61K 3135, C07D31178

Patent

active

052584020

ABSTRACT:
Imidate derivatives of sulfamates having the following formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when converted to the active agent upon administration to a mammal and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use.

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