Imaging tissue sites of inflammation

Details Imaging tissue sites of inflammation Imaging tissue sites of inflammation

1991-07-08

1994-12-27

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to lymphokine, cytokine, or other secreted growth...

424 149, 424 153, 424 169, A61K 4902

Patent

active

053763564

ABSTRACT:
The present invention involves a method of imaging tissue sites of inflammation which takes advantage of the up-regulation of surface antigenic markers on leukocytes upon activation thereof. A recognition agent selected from the group of chemotactic peptides, eosinophilic peptides and agents which are capable of selective interaction with a chemotactic receptor associated with activated leukocytes is radiolabeled. The radiolabeled recognition agent is infused into a patient and the patient's tissue sites are thereafter imaged in order to detect, evaluate or monitor tissue damage mediated by inflammation.

REFERENCES:
patent: 4348375 (1982-09-01), Goedmans
patent: 4427660 (1984-01-01), Schiffman et al.
patent: 4672044 (1987-06-01), Schreiber
patent: 4683292 (1987-07-01), Hahn
patent: 4741900 (1988-05-01), Alvarez et al.
patent: 4772584 (1988-09-01), Cleary et al.
patent: 4916118 (1990-04-01), Fidler et al.
patent: 4917878 (1990-04-01), Thakur
patent: 4926869 (1990-05-01), Rubin et al.
patent: 5110738 (1992-05-01), Takano et al.

Affiliated with

Also associated with

Rating

Imaging tissue sites of inflammation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imaging tissue sites of inflammation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imaging tissue sites of inflammation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-917253