Imaging method for spatial distributions of absorber concentrati

Surgery – Truss – Pad

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A61B 600

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056785569

ABSTRACT:
An imaging method for spatial distributions of concentrations of absorbers distributed in an object including a radiation step of applying pulsating or continuous light radiated from predetermined incident positions with predetermined wavelengths to the object in the form of a scattering medium containing the absorbers, and a detection step of detecting intensities of light passing through the object at predetermined detection positions. The imaging method also includes a step of finding a plurality photon paths for a plurality of pairs of the incident and detected positions of a model with similar dimensions to the object but without absorbers starting at the incident positions and ending at the detected positions, a step of finding averaged photon-path lengths of the photon paths starting at the incident positions and ending at the detection positions in the model by simulation, a step of finding spatial distributions of absorber concentrations from the averaged photon-path lengths, radiated intensities of the radiated light applied to the object, detected intensities of light detected at the detection positions and optical constants of the absorbers for the radiated light applied to the object, and a step of displaying the spatial distributions of the absorber concentrations.

REFERENCES:
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Science, vol. 248, pp. 990-993 "Image Reconstruction of the Interior of Bodies That Diffuse Radiation" (1990).
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BBA 42733, "Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the noninvasive . . ." pp. 184-192 (1988).
Am. Assoc. Phys. Med. vol. 10 (1983) "A Monte Carlo model for the absorption and flux distributions of light in tissue" pp. 824-830.
Journal of the Optical Society of America vol. 60 No. 8, (1970) "Absortion and Multiple Scattering by Biological Suspensions" pp. 1084-1093.
"Image reconstruction of the Interior of Bodies that Diffuse Radiation", Singer, et al, Science, vol. 248, May 25, 1990, pp. 990-993.

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