Imaging and characterization of tissue based upon the preservati

Radiant energy – Invisible radiant energy responsive electric signalling – Infrared responsive

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128664, G01N 2149

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active

057193991

ABSTRACT:
A method and apparatus for imaging and/or characterizing a tissue based upon the extent to which initially polarized light maintains its polarization after propagating through the tissue. In a preferred embodiment, the present invention relates to a method for identifying a tissue in question, the method comprising the steps of: (a) illuminating the tissue with a pulse of light, the pulse of light being polarized and having an initial state of polarization, whereby light consisting of a ballistic component, a snake-like component and a diffuse component emerges from the illuminated tissue; (b) passing the emergent light from the illuminated tissue through one of a polarizer oriented parallel to the initial state of polarization of the pulse of light and an analyzer oriented perpendicular to the initial state of polarization of the pulse of light; (c) detecting the light passed through one of the polarizer and the analyzer; and (d) comparing the detected light to appropriate standards so as to identify the type of tissue tested, i.e., breast and brain for optical mammography and tomography.

REFERENCES:
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patent: 5371368 (1994-12-01), Alfano et al.
Patterson et al., "Absorption spectroscopy in tissue-simulating materials: a theoretical and experimental study of photon paths," Applied Optics, 34(1):22-30 (Jan. 1, 1995).
Tsuchiya et al., "Photon Migration for Turbid Biological Medium Having Various Shapes," Jpn. J. Appl. Phys., 34:L79-81 (Jan. 1, 1995).

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