Image locking system for DNA micro-array synthesis

Image analysis – Applications – Biomedical applications

Reexamination Certificate

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C382S151000

Reexamination Certificate

active

07072500

ABSTRACT:
An image locking system for DNA micro-array synthesis provides a feedback system to stabilize or lock the image with respect to an image capture device, such as a camera and/or microscope. The image locking system includes the use of detection or reference marks. When a shift in image position is detected, a correction signal is sent to one of two mirrors, moving the image to correct for the shift in image position. The system comprises a first light beam directed towards a micromirror device that forms an alignment pattern on a reaction cell and a second light beam directed towards the micromirror device that forms a micro-array image on an active surface of the reaction cell. A camera captures the alignment pattern and an alignment mark. A computer calculates a correction signal to realign the alignment pattern with the alignment mark when movement is detected.

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Kerth et al, “Excimer Laser Projection Lithography on a Full-Field Scanning Projection System” IEEE, p. 299-301, 1986.

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