Image enhancement by coadministration of biomodulators and struc

Details Image enhancement by coadministration of biomodulators and struc Image enhancement by coadministration of biomodulators and struc

1991-05-01

1993-08-31

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

514 23, 424 11, 424 2, 424 9, 1286531, 1286532, 1286534, 1286535, 548453, A61K 4900, A61B 600

Patent

active

052406938

ABSTRACT:
Biomodulators can be administered together with an agent such as a drug or an imaging agent (specific or non-specific) structurally modified to take advantage of perturbations of cell oligosaccharide displays caused by biomodulators, to enhance images of a host, e.g., NMR-, X-ray- or radioimages, preferably by increasing aberrant tissue signal intensity. Biomodulators condition tissue to enhance or otherwise modify up-take of the drug or structurally modified imaging agent.

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Mann et al., "Cell Surface Oligosaccharide Modulation during Differentiation: IV. Normal and Transformed Cell Growth Control," Mechanisms of Ageing and Development, 44 (1988), pp. 17-33.

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