Image analysis system and method of biochip

Details Image analysis system and method of biochip Image analysis system and method of biochip

2006-08-01

2006-08-01

Wu, Jingge (Department: 2627)

Image analysis

Applications

Biomedical applications

C382S254000, C435S006120

Reexamination Certificate

active

07085404

ABSTRACT:
Disclosed is a biochip image analysis system which comprises an image storage unit for storing images including an original image of a biochip comprising a set of specific genes expressed in different environments by fluorescent bases of different colors; an image converter for converting the original image into a test image, forming an overlapped image and a color image, and storing the images in the image storage unit; an edge detector for separating the spot-formed genes from the test image, generating spot and background templates, and detecting an edge to measure expression degrees of the genes; a data processor for generating statistical data using the spot and background templates, and performing luminance correction; and a data storage unit for storing the statistical data.

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Brown, Carl S., et al., “Image metrics in the statistical analysis of DNA microarray data,” Proc. Nat'l. Acad. Sci. USA, vol. 98, No. 19, pp. 8944-8949.

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