Illudin analogs

Details Illudin analogs Illudin analogs

1994-11-01

1996-06-04

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C21100

Patent

active

055234909

ABSTRACT:
A compound to inhibit tumor cell growth in a subject in need of said therapy is provided, wherein said compound has the structure: ##STR1## wherein R is selected from the group consisting of: ##STR2## Tumor cells sensitive to inhibition by said compound are selected from the group consisting of a myeloid leukemia cell, a T-cell leukemia cell, a lung carcinoma cell, an ovarian carcinoma cell, and a breast carcinoma cell.

REFERENCES:
patent: 5387578 (1995-02-01), Angelucci et al.
T. C. McMorris, et al., Tet. Letts 38: 3489-3491, 1971.

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