Ileal symbiont intracellularis propagation in suspended host cel

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435245, 435366, 435383, 435395, 435403, 424 933, 424 934, 4242341, C12N 112, A61K 3902

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057143757

ABSTRACT:
A method for large scale cultivation and attenuation of IS intracellularis bacteria by inoculating cells with IS intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti-IS intracellularis vaccines are prepared from attenuated strains. Diagnostic agents are also disclosed.

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