IL-D80 polypeptides and IL-27

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000

Reexamination Certificate

active

07906622

ABSTRACT:
Purified genes encoding a cytokine or composite cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also provided.

REFERENCES:
patent: 5830451 (1998-11-01), Devergne et al.
patent: 6165461 (2000-12-01), Cobb et al.
patent: 6632624 (2003-10-01), Degorce et al.
patent: 6822082 (2004-11-01), Sheppard et al.
patent: 7579440 (2009-08-01), Timans et al.
patent: WO 94/01548 (1994-01-01), None
patent: WO 99/19491 (1999-04-01), None
patent: WO 01/70986 (2001-09-01), None
Pauline Balbas and Francisco Bolivar,Methods in Enzymology, 185:14-37, 1990. “[3] Design and Construction of Expression Plasmid Vectors inEscherichia coli”.
J. Fernando Bazan, et at,Nature, 379:591, Feb. 15, 1996. “A newly defined interleukin-1?”.
S.L. Beaucage and M.H. Caruthers,Tetrahedron Letters, 22(20):1859-1862, 1981. “Deoxynucleoside Phosphoramidites—A New Class of Key Intermediates for Deoxypolynucleotide Synthesis”.
Benjamini et al.. “Antigencity” Immunology, A Short Course, 2nded., 1992 (John Wiley & Sons, Inc.), p. 40.
M.F. Bonaldo, et al.,GenBank, Accession No. AA875330, Jul. 4, 1999. Definition: “UI-R-E0-cn-h-10- 0-UI.s1 UI-R-E0 Rattus norvegicus cDNA clone UI-R-E0-cn-h-10-0-UI 3' similar to gi|2947051|gb|AC002425|HUAC002425 Homo sapiens Chromosome 16 BAC clone CIT987SK-A575C2, complete sequence [Homo sapiens], mRNA sequence”.
Qi Chen, et al.,Nature, 407:916-920, Oct. 2000. “Development of Th1-type immune responses require the type 1 cytokine receptor TCCR”.
Q. Chen, et al.GenBank, Accession No. AF265242, Oct. 29, 2000. Definition: “Homo sapiens type-I T cell cytokine receptor mRNA, complete cds . . . ”.
Andreas D. Christ, et al.,Gastroenterology, 115:307-313, 1998. “An Interleukin 12—Related Cytokine is Up-regulated in Ulcerative Colitis but Not in Crohn's Disease”.
Odile Devergne, et al., Proc. Natl. Acad. Sci. USA, 94:12041-12046, Oct. 1997. “Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin”.
Odile Devergne, et al.,GenBank, Accession No. NM—005755, Jun. 29, 2001. Definition: “Homo sapiens Epstein-Barr virus induced gene 3 (EBI3), mRNA.”.
Alan D. Elbein,Ann. Rev. Biochem., 56:497-534, 1987. “Inhibitors of the Biosynthesis and Processing of N-Linked Oligosaccharide Chains”.
Maurice K. Gately, et al., Annu. Rev. Immunol., 16:495-521, 1998. “The Interleukin-12/Interleukin-12-Receptor System: Role in Normal and Pathologic Immune Responses”.
Herve Groux, et al.,J. Exp. Med., 184:19-29, July 1996. “Interleukin-10 Induces a Long-Term Antigen-specific Anergic State in Human CD4+ T Cells”.
Shin-ichi Hashimoto, et al.Immunobiology, 96(6):2206-2214, Sep. 15, 2000. “Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression.”.
Sten Eric W. Jacobsen,The Cytokine Handbook, 3rd ed., Ch 13:365-367, Academic Press Ltd., 1998. “Interleukin-11: A Cytokine Signaling Through gp130 with Pleiotropic Effects and Potential Clinical Utility Within and Outside the Hematopoietic System”.
Ross D. King and Michael J.E. Sternberg,Protein Science, 5:2298-2310, 1996. “Identification and application of the concepts important for accurate and reliable protein secondary structure prediction”.
Thomas A. Kunkel, et al.Methods in Enzymology, 154:367-382, 1987. “Rapid and Efficient Site-Specific Mutagenesis without Phenotypic Selection”.
B.J. Loftus, at al.,GenBank, Accession No. AC002544, Nov. 23, 1999. Definition: “Homo sapiens Chromosome 16 BAC clone CIT987SK-A-761H5, complete sequence”.
Loftus, B.J., et al., “Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q”, Database GenEmbl on STN, Loculs HUAC002544 (GenEmbl, Nov. 23, 1999).
Verne A. Luckow and Max D. Summers,Bio/technology, 6:47-55, January 1988. “Trends in the Development of Baculovirus Expression Vectors”.
M. Marra, etal.,GenBank, Accession No. AA266872, Mar. 21, 1997. Definition: “mz93e09.r1 Soares mouse lymph node NbMLN Mus musculus cDNA clone IMAGE:721000 5', mRNA sequence”.
NCI-CGAP,GenBank, Accession No. AI085007, Aug. 28, 1998. Definition: “ow88d07.r1 Soares—fetalliver—spleen 1NFLS—S1 Homo sapiens cDNA clone IMAGE:1653901 3' similar to contains element MER22 repetitive element ;, mRNA sequence”.
Saul B. Needleman and Christian D. Wunsch,J. Mol. Biol. 48:443-453, 1970. “A General Method Applicable to the Search for Similarities in the Amino Acid Sequence of Two Proteins”.
Birgit Oppmann, et al.,Immunity, 13:715-725, November 2000. “Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12”.
Patricia Parnet, et al.Journal of Biological Chemistry, 271(8):3967-70, 1996. “IL-1Rrp Is a Novel Receptor-like Molecule Similar to the Type I Interleukin-1 Receptor and Its Homologues T1/ST2 and IL-1R AcP”.
Riechmann et al. (1988)Nature332:323-327 “Reshaping human antibodies for therapy”.
Steven A. Rosenberg,Journal of Clinical Oncology, 10(2):180-199, Feb. 1992. “The Immunotherapy and Gene Therapy of Cancer”.
Burkhard Rost and Chris Sander,Proteins: Structure, Function and Genetics, 19:55-72, 1994. “Combining Evolutionary Information and Neural Networks to Predict Protein Secondary Structure”.
Martin A. Schwartz, et al.,J. of Immunotherapy, 16:95-104, 1994. “Stimulation of Cytokine Activity by Interleukin-10”.
Julie D. Thompson, et al.,Nucleic Acids Research, 25(24):4876-4882, 1997. “The CLUSTAL—X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools”.
Giorgio Trinchieri,Annu. Rev. Immunol., 13:251-276, 1995. “Interleukin-12: A Proinflammatory Cytokine With Immunoregulatory Functions That Bridge Innate Resistance And Antigen-Specific Adaptive Immunity”.
Giorgio Trinchieri,Advances in Immunology., 70:83-243, 1998. “Interleukin-12: A Cytokine at the interface of Inflammation and Immunity”.
Jean Viallet and John D. Minna,Progress in Growth Factor Research, 1:89-87, 1989. “Gastrin-Releasing Peptide (GRP, Mammalian Bombesin) In The Pathogenesis of Lung Cancer”.
Slobodan Vukicevic, et al.,Proc. Natl., Acad. Sci. USA, 93:9021-26, Aug. 1996. Induction of Nephrogenic Mesenchyme by Osteogenic Protein 1 (bone morphogenetic protein 7).
Meir Wilchek, et al.,Methods in Enzymology, 104:3-55, 1984. “[1] affinity Chromatography”.
Abbas, et al. (2000)Cellular and Molecular Immunology(4thed.), pp. 262-263, W. B. Saunders Co., NY.
Goldberg, et al. (2004)J. Immunol. 173(2):1171-1178, “Suppression of ongoing adjuvant-induced arthritis by neutralizing the function of the p28 subunit of IL-27”.
Pflanz, et al. (2004)Immunity16(6):779-790, “IL-27, a heterodimeric cytokine composed of EB13 and p28 protein, induces proliferation of naïve CD4(+) T cells”.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

IL-D80 polypeptides and IL-27 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with IL-D80 polypeptides and IL-27, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and IL-D80 polypeptides and IL-27 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2731724

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.