IL-6 specific monoclonal antibodies, hybridomas therefor and met

Details IL-6 specific monoclonal antibodies, hybridomas therefor and met IL-6 specific monoclonal antibodies, hybridomas therefor and met

1989-11-14

1997-04-08

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

4351722, 435335, 53038823, 530413, 436348, C12P 2108, C12N 520, C07K 1624, C07K 122

Patent

active

056187009

ABSTRACT:
The hybridoma 34-1 (CNCM I-813) which produces anti-human IL-6 monoclonal antibody 34-1 is disclosed. Methods of producing the monoclonal antibody and methods for affinity purification of human IL-6 using monoclonal antibody 34-1 are also described.

REFERENCES:
Novick et al. "Protides of the Biological Fluids; Proceedings of the Celloquium" vol. 32, Peeters, Ed., 1985 pp. 945-948.
Moks et al. Biotechnology 5:379-382, 1987.
Golub, "Immunology A Synthesis", Sinaur Assoc Inc 1987, pp. 19-20.
Johnstone et al. "Immunochemistry In Practice" Blackwell Sci Publ. 1987 pp. 207-240.
Goding, "Monoclonal Antibodies: Principles and Practice", Academic Press 1986, pp. 219-240.
Helle et al. J. Immunol Mtds 138:47-56, 1991.
Ida et al. Biochem Biophys Res. Comm. 165:728-734, 1989.
Van Heyningen et al., J. Immunol. Mtds vol. 62:147-153, 1983.
Novick et al., J. Gen Virol. 64:905-910, 1983.
Pluckthun, Biotechnology 9:545, 1991.
Brakenhoff et al. J. Immunology 139(12):4116-21 Dec. 15, 1987.
Campbell Monoclonal Antibody Technology Elsevier Press 1984.
Kipps et al. Handbook of Expt'l. Immunology vol. 4, Weir et al. Eds. Blackwell Sci Publ., 1986.
Zilberstein et al. EMBO Journal 5(10) 2529-37, 1986.
Weissenbach et al. PNAS USA 77:, Dec. 1980, 7152-7156.
Van Damme et al. J. Immunology 140(5) 1534-41 Mar. 1, 1988.
Matsuda, T. et al. "Establishment of an interleukin 6(IL6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL6 monoclonal antibodies", Eur. J. Immunol., 18, 951-956 (1988).
Novick, D. et al., "Monoclonal antibody for purification and RIA of natural and recombinant human IFN-a, B and gamme", CA. No. 129976b, vol. 102, No. 15, p. 454, Apr. 15, 1985.
Suji, M. et al., "Monoclonal antibody to human beta interferon: Characterization and application", Biological Abstracts, No. 47888, vol. 85, No. 5, 1988.

Affiliated with

Also associated with

Rating

IL-6 specific monoclonal antibodies, hybridomas therefor and met does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with IL-6 specific monoclonal antibodies, hybridomas therefor and met, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and IL-6 specific monoclonal antibodies, hybridomas therefor and met will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2397244