IL-6 as serum uric acid decreasing compound

Details IL-6 as serum uric acid decreasing compound IL-6 as serum uric acid decreasing compound

1998-02-23

1999-12-28

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

930141, 514 2, 530351, A61K 3820, A61K 3800

Patent

active

060078049

ABSTRACT:
The present invention provides a serum uric acid decreasing agent which contains interleukin-6 (IL-6) as the active ingredient together with a pharmaceutically acceptable carrier; and a method for decreasing the serum uric acid level which comprises administering interleukin-6 (IL-6) in an effective amount to a patient.

REFERENCES:
Yoshio et al. Purin, Pirimijin Taisha, 21(1), 48-49, Jan. 1997.
Brozik et al. J Rheumatol 19 (1), 63-68, Jan. 1992.
Weber, J. et al., Phase I Trial of Subcutaneous Interleukin-6 in Patients with Advanced Malignancies, J. Clin. Oncology, 11(3), Mar. 1993, pp. 499-506.
Hirano, T., et al., Purification To Homogeneity and Characterization of Human B-cell Differentiation Factor (BCDF or BSFp-2), Proc. Nat. Acad. Sci. USA, 82, Aug. 1985, pp. 5490-5495.
Kishimoto, T., The Biology of Interleukin-6, Blood, 74(1), Jul. 1989, pp. 1-10.

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