Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1996-04-09
2000-02-15
Chambers, Jasemine C.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
4351723, 435 691, 435 6952, 435 912, 4353201, 435325, 536 235, 536 2431, 424 92, C12N 500, C12N 1500, C12N 1509
Patent
active
060255390
ABSTRACT:
A transgenic mouse is provided, the cells of which contain and express IL-5 in a cell type- or tissue-specific manner and in an amount which results in an IL-5-associated pathology. Also provided are expression cassettes comprising an IL-5 gene, operably linked to a cell type- or tissue-specific transcriptional control sequence and methods of using transgenic mice comprising the expression cassettes.
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Lee James J.
Lee Nancy A.
Chambers Jasemine C.
Mayo Foundation for Medical Education and Research
Schmuck Jill D.
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