Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...
Patent
1995-03-15
1997-03-25
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
4341341, 4341381, 4341831, 435 723, 435 696, 5303873, 5303877, 5303913, 5303917, A61K 39395, C07K 1646, G01N 3353
Patent
active
056141912
ABSTRACT:
The present invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell. The method involves providing a chimeric molecule that comprises an effector molecule attached to a targeting molecule that specifically binds an IL-13 receptor and contacting a tumor cell with the chimeric molecule.
REFERENCES:
patent: 5082927 (1992-01-01), Pastan et al.
Thrush et al 1996 Ann Rev Immunol vol. 14 49-71.
Obiri et al. (1995). J. Biol. Chem vol. 270, No. 15:8797.
Debinski et al. (1993) J. Biol. Chem vol. 268 No. 19:14065.
Debinski et al. (1994). Bioconjugate Chem vol. 5:40-46.
Chester et al (1995) Tibtech vol. 13:294-300.
Gottstein et al (1994) Annab of Oncology vol. 5 Supplement 1: S97-103.
Vita et al., Journ. of Biol. Chem., 270:3512 (1995).
Chaudhary et al., Nature, 339: 394-397 (1989).
McKenzie et al. Proc. Natl. Acad. Sci. USA, 90: 3735 (1993).
Pastan et al., Ann. Rev. Biochem., 61: 331-354 (1992).
Minty et al., Nature, 362: 248 (1993).
Debinski Waldemar
Obiri Nicholas
Pastan Ira
Puri Raj K.
Nucker Christine M.
Reeves Julie E.
The United States of America as represented by the Department of
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