IL-13 receptor specific chimeric proteins and uses thereof

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4341341, 4341381, 4341831, 435 723, 435 696, 5303873, 5303877, 5303913, 5303917, A61K 39395, C07K 1646, G01N 3353

Patent

active

056141912

ABSTRACT:
The present invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell. The method involves providing a chimeric molecule that comprises an effector molecule attached to a targeting molecule that specifically binds an IL-13 receptor and contacting a tumor cell with the chimeric molecule.

REFERENCES:
patent: 5082927 (1992-01-01), Pastan et al.
Thrush et al 1996 Ann Rev Immunol vol. 14 49-71.
Obiri et al. (1995). J. Biol. Chem vol. 270, No. 15:8797.
Debinski et al. (1993) J. Biol. Chem vol. 268 No. 19:14065.
Debinski et al. (1994). Bioconjugate Chem vol. 5:40-46.
Chester et al (1995) Tibtech vol. 13:294-300.
Gottstein et al (1994) Annab of Oncology vol. 5 Supplement 1: S97-103.
Vita et al., Journ. of Biol. Chem., 270:3512 (1995).
Chaudhary et al., Nature, 339: 394-397 (1989).
McKenzie et al. Proc. Natl. Acad. Sci. USA, 90: 3735 (1993).
Pastan et al., Ann. Rev. Biochem., 61: 331-354 (1992).
Minty et al., Nature, 362: 248 (1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

IL-13 receptor specific chimeric proteins and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with IL-13 receptor specific chimeric proteins and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and IL-13 receptor specific chimeric proteins and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2201078

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.