IL-12 for expression in mammalian cell

Details IL-12 for expression in mammalian cell IL-12 for expression in mammalian cell

2007-01-12

2010-11-16

Bunner, Bridget E (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S471000, C536S023500, C530S351000

Reexamination Certificate

active

07833754

ABSTRACT:
The present invention provides for nucleic acids improved for the expression of interleukin-12 (IL-12) in mammalian cells. The invention further provides for methods of expressing IL-12 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-12 sequence.

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Jayaray et al., “GeMS: an advanced software package for designing synthetic genes,” 2005, Nucleic Acids Res.,; 33: 3011-3016.

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