IL-1 receptor based cytokine traps

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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Details

C435S320100, C435S252300, C435S255100, C435S348000, C435S361000, C530S350000, C514S012200, C536S023500

Reexamination Certificate

active

06927044

ABSTRACT:
Fusion polypeptides capable of binding interleukin-1 (IL-1) to form a nonfunctional complex are provided and nucleic acid molecules encoding the fusion polypeptides. The fusion ploypeptides form dimers to function as IL-1 antagonists.

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