IL-1 receptor accessory protein

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C530S300000

Reexamination Certificate

active

11387672

ABSTRACT:
DNA encoding IL-1R AcP splice variant polypeptides, the polypeptides and methods for using the encoded polypeptides are disclosed.

REFERENCES:
patent: WO97 23067 (1996-08-01), None
Cao, Z., GenBank, Accession No. AR166115, 2001.
Greenfeder et al., “Molecular cloning a characterization of a second subunit of the interleukin 1 receptor complex”,J. Biol. Chem. 270(23):13757-13765, 1995.
Huang et al., “Recuitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein”,Proc. Natl. Acad. Sci. USA 94:12829-12832, 1997.
Huang et al., GenBank, Accession No. AF029213, Sep. 30, 1999.
Jensen, et al., “IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory proteins,”J. of Immunol. 164(10):5277-5286, 2000.
Parnet et al., “IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP,”J. of Biol. Chem. 271(8):3967-3970, 1996.
Sims et al., “A new nomenclature for IL-1-family genes,”Trends in Immunol. 22(10):536-537, 2001.

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