IKAP nucleic acids

Details IKAP nucleic acids IKAP nucleic acids

1997-11-16

1999-04-06

Feisee, Lila

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4352523, 43525411, 435 691, 536 235, 536 231, 536 243, 536 2431, 530300, 530350, C12N 510, C12N 1512, C12N 1511, C07K 1447

Patent

active

058917195

ABSTRACT:
The invention provides methods and compositions relating to IKAP proteins which regulate cellular signal transduction and transcriptional activation, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IKAP encoding nucleic acids or purified from human cells. The invention provides isolated IKAP hybridization probes and primers capable of specifically hybridizing with the disclosed IKAP genes, IKAP-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.

REFERENCES:
Hillier, et al. Accession No. W52507, Database: Genebank-EST, May 31, 1996.
Darnell, et al. in Molecular Cell Biology. p. 641, Scientific American Books, Inc., New York, NY, 1986.
GenBank Accession No. H19711, Hillier et al., accessed Oct. 28, 1998, Jul. 1995.
GenBank Accession No. H15327, Hillier et al., accessed Oct. 28, 1998, Jun. 1995.
GenBank Accession AA455598, "aa17d06.rl" Soares NhHMPu S1 Homo sapeins cDNA clone 813515 5', accessed 04 Nov. 1998, Jun. 1997.
GenBank Accession AA324126, EST27019 cerebellum II Homo sapeins cDNA 5' end, accessed 04 Nov. 1998, Apr. 1997.
GenBank Accession AA478782, zv20c02.sl Soares NhHMPu S1 Homo sapeins cDNA clone 754178 3', accessed 04 Nov. 1998, Aug. 1997.
GenBank Accession AA478782, zv20c02.rl Soares NhHMPu S1 Homo sapeins cDNA clone 754178 5', accessed 04 Nov. 1998, Aug. 1997.
Adams et al., Initial assessment of human gene diversity and expression patterns based on 83 million nucleotides of cDNA sequence, Nature 377 (Supp.):3-174, pp. 3-17, Sept. 1995.

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