IgE Fc directed delivery system

Details IgE Fc directed delivery system IgE Fc directed delivery system

1986-07-22

1990-02-20

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

530387, 530388, 530402, 424 9, 424 8591, A61K 4902, A61K 39395

Patent

active

049024957

ABSTRACT:
An immunotoxin comprising a conjugate of a toxin with immunoglobulin E or a part thereof and a method delivering the same to a target site is described. Mast cell related abnormalities can be detected by the immunotoxin of the present invention.

REFERENCES:
patent: 4331647 (1982-05-01), Goldenberg
patent: 4348376 (1982-09-01), Goldenberg
patent: 4361544 (1982-11-01), Goldenberg
patent: 4624846 (1986-11-01), Goldenberg
patent: 4683292 (1987-07-01), Hahn
Refsnes et al. (1976), J. Exp. Med., 143:1464-1474.
Boltansky et al. (1985), Abstract #320, published in Journal of Allergy and Clinical Immunology, Supplement vol. 75.
Boltansky et al. (1985), Abstract for FASEB Reports, "A Selective Immunotoxin for IgE-Fc Receptor Positive Cells".

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