IgA Fc receptors

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 691, C07K 1300

Patent

active

053289870

ABSTRACT:
The present invention provides an isolated DNA sequence encoding soluble and membrane bound forms of a mammalian IgA Fc receptor, as well as recombinant expression vectors and host cells suitable for expressing the protein.

REFERENCES:
patent: 4675285 (1987-06-01), Clark et al.
Mestecky et al., "Immunoglobulin A (IgA): Molecular and Cellular Interactions Involved in IgA Biosynthesis and Immune Response," Advances in Immunology 40:153, 1987.
P.N.A.S. 83: 6980-6984, Sep. 1986, Hobbs et al. The Murile Fc Receptor for Immuno Globulin: Purification, Partial Amino Acid Sequence, and Isolation of CDNA Clones.
Underdown et al., Ann. Rev. Immunol. 4:489, 1986 "Immunoglobulin A: Strategic Defense Initiative at the Mucosal Surface".
Fanger et al., "Subpopulations of human peripheral granulocytes and monocytes express receptors for IgA," Proc. Natl. Acad. Sci. 77:3640, 1980.
Gauldie et al., "Fc Receptors for IgA and Other Immunoglobulins on Resident and Activated Alveolar Macrophages," Molec. Immunol. 20:1029, 1983.
Maliszewski et al., "The Expression of Receptors for IgA on Human Monocytes and Calcitriol-treated HL-60 Cells," J. Immunol. 135:3878, 1985.
Chevailler, et al., "Immunofluorescence Analysis of IgA Binding by Human Mononuclear Cells in Blood and Lymphoid Tissue," J. Immunol. 142:2244, 1989.
Fanger et al., "Cytofluorographic Analysis of Receptors for IgA on Human Polymorphonuclear Cells and Monocytes and the Correlation of Receptor Expression with Phagocytosis," Molec. Immunol. 20:1019, 1983.
Shen, et al., "IgA-Mediated Effector Function of HL-60 Cells Following Treatment with Calcitriol," Molec. Immunol. 23:611, 1986.
Ferreri et al., "Release of Leukotrienes C.sub.4 and B.sub.4 and Prostaglandin E.sub.2 from Human Monocytes Stimulated with Aggregated IgA, IgA, and IgE," J. Immunol. 136:4188, 1986.
Albrechtson et al., Immunology 64:201, 1988 "Characterization of the IgA Receptor from Human Polymorphonuclear Leukocytes".
Monteiro et al., "Cellular Distribution, Regulation and Biochemical Nature of an Fc-alpha Receptor in Humans," J. Exp. Med. 171:597, 1990.
Kiyono et al., "Isotype-Specific Immunoregulation," J. Exp. Med. 161:731 (1985).
Bich-Thuy and Revillard, "Only T-alpha or T-gamma cells can be triggered by IgG or IgA to suppress the production of the matching Ig class," Eur. J. Immunol. 16:156, 1986.
Moore, et al., "Defective T Cell-Mediated, Isotype-Specific Immunoglobulin Regulation in B Cell Chronic Lymphocytic Leukemia," Blood 71:1012, 1988.
Dunkley, et al., Cognate T-cell help in the induction of IgA responses in vivo, Immunology 71:16, 1990.
Moore and Hoover, "Defective Isotype-Specific Regulation of IgA Anti-Erythrocyte Autoantibody-Forming Cells in NZB Mice," J. Immunol. 142:4282, 1989.
Yodoi et al., "Induction of FcR-alpha on Murine Lymphocytes by IgA in vitro," J. Immunol. 128:888, 1982.
Endoh et al., "Communications: IgA-Specific Helper Activity of T-alpha Cells in Human Peripheral Blood," J. Immunol. 127:2612, 1981.
Yodoi et al., "T-Cell Hybridomas Co-Expressing Fc Receptors (FcR) for Different Isotypes," J. Immunol. 131:303, 1983.
Adachi et al., "Murine IgA Binding Factors Produced by Fc-alphaR(+) T Cells: Role of Fc-gammaR(+) Cells for the induction of Fc-alphaR and Formation of IgA Binding Factor in Con A-Activated Cells," J. Immunol. 133:65, 1984.
Noro et al., "Murine IgA Binding Factors (IgA-BF) Suppressing IgA Production: Characterization and Target Specificity of IgA-BF," J. Immunol. 136:2910 1986.
Hoover and Lynch, "Isotype-Specific Suppression of IgA: Suppression of IgA Responses in BALB/c Mice by T-alpha Cells," J. Immunol. 130, 1983.
Word et al., "Regulations of IgA Expression by Isotype-Specific T Cells and Soluble Binding Factors," Ann. Rev. Microbiol. 40:503, 1986.
Shen and Fanger, "Secretory IgA Antibodies Synergize with IgG in Promoting ADCC by Human Polymorphonuclear Cells, Monocytes and Lymphocytes," Cell 59:75, 1981.
Millet et al., "Expression of receptors for IgA on mitogenstimulated human T lymphocytes", Eur. J. Immunol. 18:621, 1988.
Sims et al., "cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily", Science 241:585, 1988.
Shen et al., "A monoclonal antibody that reacts with human myeloid cells, inhibits monocyte IgA binding and triggers function", J. Immunol. 143:4117, 1989.
Seed et al., "Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure", Proc. Natl. Aca. Sci. USA 84:3365, 1987.
Smith et al., "Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen", Science 238:1704, 1987.
Gearing et al., EMBO J. 8:3667, 1989.
Aruffo et al., Proc. Natl. Acad. Sci. USA 84:8573, 1987.
Yang et al., Cell 47:3, 1986.
Yamasaki et al., Science 241:825, 1988.
Cosman, DNA Pro. Eng. Tech. 2:1, 1990.
Blank et al., Nature 337:1989.
Ravetch and Kinet, Ann. Rev. Immunol. 9:457, 1991.
Maliszewski et al., J. Exp. Med. 172:1665, 1990.
Monteiro et al., J. Immunol. 148:1764, 1992.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

IgA Fc receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with IgA Fc receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and IgA Fc receptors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-397297

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.