Ifosfamide-mesna lyophilizate and process for its preparation

Details Ifosfamide-mesna lyophilizate and process for its preparation Ifosfamide-mesna lyophilizate and process for its preparation

1989-03-20

1990-09-25

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424423, A61K 900

Patent

active

049592157

ABSTRACT:
An ifosfamide-mesna lyophilizate consists substantially of ifosfamide, 0.1-1.0 parts by weight of mesna and 0.1 to 17 parts by weight of hexitol. The product is obtained by freeze drying an aqueous or aqueous-ethanolic solution of ifosfamide and mesna.

REFERENCES:
patent: 4623742 (1986-11-01), Scheffler et al.
patent: 4716242 (1987-12-01), Engel et al.
patent: 4859452 (1989-08-01), Ajani et al.
patent: 4871528 (1989-10-01), Tognella et al.

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