IFN receptor 1 binding proteins, DNA encoding them, and...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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Details

C435S070100, C435S320100, C435S325000

Reexamination Certificate

active

10309280

ABSTRACT:
Novel proteins IR1B1 and IR1B4 have been isolated which bind to the type I IFN receptor IFNAR1 and function in the cellular response to IFNs. DNA encoding such proteins in either the sense or anti-sense orientation can be administered to either enhance or inhibit the cellular response to IFNs. Antibodies to the proteins can be used for isolation of the new protein or for immunodetection thereof.

REFERENCES:
patent: 5981181 (1999-11-01), Frommer et al.
patent: 6242587 (2001-06-01), Naik et al.
patent: 0 679 717 (1995-11-01), None
patent: WO98/14471 (1998-04-01), None

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