Identifying modulators of fibroblast growth factor-like...

Details Identifying modulators of fibroblast growth factor-like... Identifying modulators of fibroblast growth factor-like...

2010-06-01

2011-10-25

Saoud, Christine J (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C435S320100, C435S007100

Reexamination Certificate

active

08044024

ABSTRACT:
The present invention provides novel Fibroblast Growth Factor-like (FGF-like) polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies and methods for producing FGF-like polypeptides. Also provided for are methods for the diagnosis and treatment of diseases associated with FGF-like polypeptides.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4179337 (1979-12-01), Davis et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4892538 (1990-01-01), Aebischer et al.
patent: 4945050 (1990-07-01), Sanford et al.
patent: 4970154 (1990-11-01), Chang
patent: 5011472 (1991-04-01), Aebischer et al.
patent: 5106627 (1992-04-01), Aebischer et al.
patent: 5217889 (1993-06-01), Roninson et al.
patent: 5234784 (1993-08-01), Aslam et al.
patent: 5252714 (1993-10-01), Harris et al.
patent: 5272071 (1993-12-01), Chappel
patent: 5364791 (1994-11-01), Vegeto et al.
patent: 5489743 (1996-02-01), Robinson et al.
patent: 5557032 (1996-09-01), Mak
patent: 5589362 (1996-12-01), Bujard et al.
patent: 5593875 (1997-01-01), Wurm et al.
patent: 5635399 (1997-06-01), Kriegler et al.
patent: 5650298 (1997-07-01), Bujard et al.
patent: 5654168 (1997-08-01), Bujard et al.
patent: 5672510 (1997-09-01), Eglitis et al.
patent: 5676954 (1997-10-01), Brigham
patent: 5679559 (1997-10-01), Kim et al.
patent: 5811234 (1998-09-01), Roninson et al.
patent: 6150098 (2000-11-01), Zhang
patent: 6639063 (2003-10-01), Edwards
patent: 6716626 (2004-04-01), Itoh
patent: 7259248 (2007-08-01), Itoh
patent: 2001/0012628 (2001-08-01), Agarwal et al.
patent: 2007/0128619 (2007-06-01), Itoh
patent: 2007/0238657 (2007-10-01), Itoh
patent: 0036676 (1981-09-01), None
patent: 0058481 (1982-08-01), None
patent: 0088046 (1983-09-01), None
patent: 0133988 (1985-03-01), None
patent: 0143949 (1985-06-01), None
patent: 0154316 (1985-09-01), None
patent: 0401384 (1990-12-01), None
patent: 0505500 (1992-09-01), None
patent: WO 91/09955 (1991-07-01), None
patent: WO 91/10425 (1991-07-01), None
patent: WO 91/10470 (1991-07-01), None
patent: WO 93/15722 (1993-08-01), None
patent: WO 94/20069 (1994-09-01), None
patent: WO 94/28122 (1994-12-01), None
patent: WO 95/05452 (1995-02-01), None
patent: WO 95/34670 (1995-12-01), None
patent: WO 96/37609 (1996-11-01), None
patent: WO 96/40958 (1996-12-01), None
patent: WO 96/41865 (1996-12-01), None
patent: WO 97/31899 (1997-09-01), None
patent: WO 00/54813 (2000-09-01), None
patent: WO 01/18209 (2001-03-01), None
patent: WO 01/32678 (2001-05-01), None
patent: WO 01/36640 (2001-05-01), None
patent: WO 01/38357 (2001-05-01), None
patent: WO 01/49849 (2001-07-01), None
The ADHR consortium (2000), “Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23.” Nature Genetics 26: 345-348.
Artuc et al. (1999), “Mast cells and their mediators in cutaneous wound healing—active participants or innocent bystanders?” Exp. Dermatol. 8: 1-16.
Beck and Podolsky (1999), “Growth factors in inflammatory bowel disease.” Inflamm. Bowel Dis. 5: 44-60.
Bishop (1996), “Chromosomal insertion of foreign DNA,” Reprod. Nutr. Dev. 36(6): 607-18.
Bork et al. (1996), “Go hunting in sequence databases but watch out for the traps,” Trends Genet. 12(10): 425-27.
Bork et al. (1998), “Predicting functions from protein sequences—where are the bottlenecks?” Nature Genetics 18(4): 313-18.
Bork (2000), “Powers and pitfalls in sequence analysis: the 70% hurdle,” Genome Res. 10(4): 398-400.
Branch (1998), “A good antisense molecule is hard to find.” Trends Biochem Sci. 23(2): 45-50.
Brenner (1999), “Errors in genome annotation,” Trends Genet. 15(4): 132-33.
Cunha et al. (1996), “Keratinocyte growth factor as mediator of mesenchymal-epithelial interactions in the development of androgen target organs.” Semin Cell Dev Biol 7: 203-210.
Doerks et al. (1998), “Protein annotation: detective work for function prediction,” Trends Genet. 14(6): 248-50.
Ebadi et al. (1997), “Neurotrophins and their receptors in nerve injury and repair.” Neurochem. Int. 30: 347-74.
Econs and Mcenery. “Autosomal dominant hypophosphatemic rickets/osteomalacia: clinical characterization of a novel renal phosphate-wasting disorder.” J Clin Endocrinol Metab 82:674-681 (1997).
Faham et al. (1998), “Diversity does make a difference: fibroblast growth factor-heparin interactions,” Curr. Opin. Struct. Biol. 8(5): 578-86.
Galzie Z. et al. (1997), “Fibroblast Growth Factors and their Receptors”, Biochemistry and Cell Biology 75(6): 669-685.
GenBank Acc. No. AB006136, Aug. 27, 1997.
GenBank Acc. No. AQ175436, Sep. 21, 1998, accessed Nov. 18, 2005.
GenBank Acc. No. AV050323, Jun. 16, 1999, accessed Nov. 18, 2005.
GenBank Acc. No. BAA99415, Aug. 3, 2000.
GenBank Acc. No. BAA99416, Jul. 11, 2000.
GenBank Acc. No. NP—061986, Apr. 6, 2003.
GenBank Acc. No. Q9NSA1, Oct. 1, 2000.
Ghielli et al. (1998), “Regeneration processes in the kidney after acute injury: role of infiltrating cells.” Exp. Nephrol. 6: 502-507.
Goldfarb (1996), “Functions of fibroblast growth factors in vertebrate development,” Cytokine Growth Factor Rev. 7 (4): 311-325.
Hoppenreijs et al. (1996), “Corneal endothelium and growth factors.” Surv. Ophthalmol. 41: 155-64.
Hull et al (1997), “Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration,” Gut 40: 204-10.
Hsu et al. (1999), “Heparin Is Essential for a Single Keratinoctye Growth Factor Molecule To Bind and Form a Complex with Two Molecules of the Extracellular Domain of Its Receptor,” Biochemistry 38: 2523-34.
Hu et al., (1998), “FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation,” Mol. Cell. Biol. 18(10): 6063-6074.
Itoh and Ornitz (2004), “Evolution of the FGF and FGFR gene families.” Trends in Genetics 20(11): 563-569.
Kaufman et al. (1999), “Transgenic analysis of a 100-kb human beta-globin cluster-containing DNA fragment propagated as a bacterial artificial chromosome.” Blood 94: 3178-3184.
Kennell (1971), “Principles and practices of nucleic acid hybridization,” Progr. Nucl. Acid Res. Mol. Biol. 11: 259-301.
Kharitonenkov et al. (2005), “FGF-21 as a novel metabolic regulator.” J. Clin. Invest. 115: 1627-1635.
Kornmann et al. (1998), “Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis.” Pancreas 17: 169-75.
Kurosu et al. (2007), “Tissue-specific Expression of Klotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21.” J. Biol. Chem. 282(37): 26687-26695.
Ledley (1996), “Pharmaceutical Approach to Somatic Gene Therapy.” Pharm. Res. 13(11): 1595-1614.
Lewis el al. (1997), “Angiogenesis by gene therapy: a new horizon for myocardial revascularization?” Cardiovasc. Res. 135: 490-497.
Liu et al. (2007), “FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.” Dev. Biol. 302: 80-91.
Mahairas et al. (1999), “Sequence-tagged connectors: a sequence approach to mapping and scanning the human genome.” PNAS 96(17): 9739-9744.
Mikkelsen (1993), “Interpreting seqeunce motifs: a cautionary note,” Trends Genet. 9(5): 159.
Nakamura et al. (1995), “The murine lymphotoxin-beta receptor cDNA: isolation by the signal sequence trap and chromosomal mapping,” Genomics 30(2): 312-19.
Ngo et al. (1994), “Computational complexity, protein structure prediction, and the Levinthal paradox,” in The Protein Folding Problem and Tertiary Structure Prediction, Merz &

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