Identification of viral agents in breast ducts and antiviral...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S184100, C435S005000, C435S007100, C435S007230

Reexamination Certificate

active

07132232

ABSTRACT:
Methods and systems for identifying a virus in breast ducts are provided. In addition, antiviral therapy for treating a virally infected breast duct is also provided. Patients with a viral infection identified in the breast ducts may be at risk for developing breast precancer or cancer.

REFERENCES:
patent: 5169774 (1992-12-01), Frankel et al.
patent: 5677171 (1997-10-01), Hudziak et al.
patent: 5720937 (1998-02-01), Hudziak et al.
patent: 5725856 (1998-03-01), Hudziak et al.
patent: 5763415 (1998-06-01), Sukumar
patent: 6221622 (2001-04-01), Love
patent: 6413228 (2002-07-01), Hung et al.
patent: 0 502 485 (1996-10-01), None
patent: WO 99-55384 (1999-11-01), None
patent: WO 00 42841 (2000-07-01), None
patent: WO 00 51666 (2000-09-01), None
Androphy E.J. Papillomaviruses and interferon. Ciba Foundation Symposium (1986) vol. 120, pp. 221-234.
Noguchi et al. Clonal analysis of solitary intraductal papilloma of the breast by means of polymerase chain reaction. American Journal of Pathology (1994) vol. 144, No. 6, pp. 1320-1325.
Gross G. Therapy of human papillomavirus infection and assoicated epithelial tumors. Intervirology (1997) vol. 40, pp. 368-377.
Evron et al. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR. The Lancet (Apr. 2001) vol. 35 pp. 1335-1336.
HPV33 DNA In Premalignant and Malignant Breast Lesions in Chinese and Japanese Populations, Anticancer Research, Nov. 1999, pp. 5057-5062, vol. 19, No. 6B, XP001022307.
G.J. Hammons, “Increased expression of hepatic DNA methyltransferase in smokers”, Cell Biol Toxicol, 1999; 15(6), pp. 389-394, Abstract Only.
F.E. Domann et al., “Epigenetic silencing of maspin gene expression in human breast cancers”, Int. J. Cancer, Mar. 15, 2000; 85(6), pp. 805-810, Abstract Only.
B.K. Nayak et al, “Mutation and methylation status of p53 gene promoter in human breast tumours”, Tumour Biol. Nov.-Dec./1999, 20(6), pp. 341-346, Abstract Only.
Y.I. Kim, “Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects”, Nutr. Rev., Oct. 1999, 57(10), pp. 314-321, Abstract Only.
S.J. Nass et al., “Expression of DNA methyl-transferase (DMT) and the cell cycle in hman breast cancer cells”, Oncogene, Dec. 9, 1999, 18(52) pp. 7453-7461, Abstract Only.
M. Esteller, “Epigenetic lesions causing genetic lesions in human cancer. promoter hypermethylation of DNA repair genes”, Eur J Cancer, Dec. 2000, 36(18), pp. 2294-2300, Abstract Only.
S.S. Dehal et al., “The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy”, Drug Metab Dispos, Mar. 1999, 27(3), pp. 389-394, Abstract Only.
Leborgne, Intraductal Biopsy of Certain Pathologic Processes of the Breast, Surgery 19:47-54 (1946).
Papanicolaou et al., Exfoliative Cytology of the Human Mammary Gland and Its Value in the Diagnosis of Cancer and Other Diseases of the Breast, Cancer 11:377-409 (1958).
Buehring, Screening for Breast Atypias Using Exfoliative Cytology, Cancer 43(5):1788-1799 (1979).
Makita et al., Duct Endoscopy and Endoscopic Biopsy in the Evaluation of Nipple Discharge, Breast Cancer Research and Treatment 18:179-188 (1991).
Jin et al., Study of Tumor Markers in Mammary Ductal Lavage for Early Detection of Breast Carcinoma, Zhongguo Zhong Liu Lin Chuang 23(6):381-385 (1996),with English translation.
Love et al., Breast-Duct Endoscopy to Study Stages of Cancerous Breast Disease, Lancet 348:997-999 (1996).
Sauter et al., Nipple Aspirate Fluid: A Promising Non-Invasive Method to Identify Cellular Markers of Breast Cancer Risk, British J. Cancer 76(4):494-501 (1997).
M. Widschwendter et al., “Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer”, J. National Cancer Institute, May 17, 2000; 92(10), pp. 826-832, Abstract Only.
K.E. Conway et al., “TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers”, Cancer Research, Nov. 15, 2000, 60(22), pp. 6236-6242, Abstract Only.
K.M. Lau, “Expresion of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation”, Cancer Research, Jun. 15, 2000, 60(12), pp. 3175-3182, Abstract Only.
A. Vilain et al., “DNA methylation and chromosome instability in breast cancer cell lines”, FEBS Lett, Oct. 29, 1999, 460(2), pp. 231-234, Abstract Only.
S. M. Sirchia et al., “Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells”, Oncogene, Mar. 16, 2000. 19(12), pp. 1556-1563, Abstract Only.
S. Milutinovic et al., “DNA Methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1)”, J. Biological Chem., Mar. 3, 2000, 275(9), pp. 6353-6359, Abstract Only.
P.M. Warnecke et al., “Cytosine methylation and human cancer”, Curr. Opin. Oncol, Jan. 2000, 12(1), pp. 68-73, Abstract Only.
J. Song et al., “Chemopreventive effects of dietary folate on intestinal polyps in Apc+/−Msh2−/−- mice”, Cancer Research, Jun. 15, 2000, 60(12), pp. 3191-3199, Abstract Only.
Y. NIWA et al, “BRCA1 Expression Status in Relation to DNA Methylation of the BRCA1 Promoter Region in Sporadic Breast Cancers, ” Jpn J. Cancer Research, May 2000 , 91(5), pp. 519-526, Abstract Only.
R.G. Lapidus et al., “The loss of estrogen and progesterone receptor gene expression in human breast cancer”, J. Mammary Gland Biol. Neoplasia, Jan. 1998, 3(1), pp. 85-94, Abstract Only.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Identification of viral agents in breast ducts and antiviral... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Identification of viral agents in breast ducts and antiviral..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Identification of viral agents in breast ducts and antiviral... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3659543

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.