Identification of the gene and mutation responsible for...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091100, C435S091200, C536S023100, C536S024300

Reexamination Certificate

active

11157743

ABSTRACT:
Tools and methods are provided for determining whether or not a dog is genetically normal, is a carrier of, or is affected with or predisposed to progressive rod-cone degeneration. The method is based on the detection of a transversion from G to A at position corresponding to nucleotide position 1298 of SEQ ID NO: 1.

REFERENCES:
patent: 5804388 (1998-09-01), Aguirre et al.
patent: WO 9902731 (1999-01-01), None
patent: WO 0029615 (2000-05-01), None
Acland, Gregory M. et al., “A Novel Retinal Degeneration Locus Identified by Linkage and Comparative Mapping of Canine Early Retinal Degeneration”, GENOMICS, 199, pp. 134-142, vol. 59, Academic Press, San Diego, U.S.A.
Caase, C., et al., “A Gene Potentially Involved in Progressive Rod—Con Degeneration (PRCD)”, Annual Meeting of the Association for Research in Vision and Opthalmology, May 2003, Abstract No. 2318, vol. 2003, Biosis Online Biosciences Information Service, Philadelphia, U.S.A.
Sargan David et al., Use of Flow-Sorted Canine Chromosomes in the Assignment of Canine Linkage, Radiation Hybrid, and Syntenic Groups to Chromosomes: Refinement and Verification of the Comparative Chromosome Map for Dog and Human, GENOMICS, Oct. 15, 2000, pp. 182-195, vol. 69, No. 2, Academic Press, San Diego, U.S.A.
Sidjanin, D.J. et al., “Radiation Hybrid Map, Physical Map, and Low-Pass Genomic Sequence of the Canine prcd Region on CFA9 and Comparative Mapping with the Syntenic Region on Human Chromosome 17”, GENOMICS, 2003, 2003, pp. 138-148, vol. 81, Academic Press, San Diego, U.S.A.

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