Combinatorial chemistry technology: method – library – apparatus – Method of creating a library – Solid-phase synthesis or particular method of cleavage from...
Reexamination Certificate
2011-07-05
2011-07-05
Lundgren, Jeffrey S. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method of creating a library
Solid-phase synthesis or particular method of cleavage from...
C506S007000, C506S013000, C506S023000
Reexamination Certificate
active
07972993
ABSTRACT:
The invention relates to the field of molecular recognition or detection of discontinuous or conformational binding sites or epitopes corresponding to a binding molecule, in particular, in relation to protein-protein, protein-nucleic acid, nucleic acid-nucleic acid or biomolecule-ligand interactions. The invention provides a synthetic molecular library allowing testing for, identification, characterization or detection of a discontinuous binding site capable of interacting with a binding molecule, the library having been provided with a plurality of test entities, each test entity comprising at least one first segment spotted next to a second segment, each segment having the capacity of being a potential single part of a discontinuous binding site.
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Dijk Evert van
Meloen Robbert Hans
Puijk Wouter Cornelis
Slootstra Jelle Wouter
van Dijken Pieter
Lundgren Jeffrey S.
Pepscan Systems B.V.
TraskBritt P.C.
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