Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2011-06-14
2011-06-14
Noakes, Suzanne M (Department: 1656)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C702S027000, C703S011000, C435S007710
Reexamination Certificate
active
07962290
ABSTRACT:
The invention comprises for methods of identifying pharmacophores based on the spleen tyrosine kinase (SYK) protein or fragment thereof. The invention further provides methods of identifying SYK inhibitors using pharmacophores that are identified from co-crystals of SYK and its ligands. Further, the invention comprises methods of inhibiting SYK comprising contacting the residues lining the binding site with an inhibitor compound identified from pharmacophores.
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Lee Jae W
McDonnell Boehnen & Hulbert & Berghoff LLP
Noakes Suzanne M
Rigel Pharmaceuticals Inc.
Young Travis
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