Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-12-02
1997-06-17
Chambers, Jasemine C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 5, 4351723, 536 241, 536 243, 536 2432, C12Q 170, C12Q 168, C07H 2102, C07H 2104
Patent
active
056395957
ABSTRACT:
Methods for identifying oligonucleotides having a desired activity in vivo are disclosed. In accordance with preferred embodiments, oligonucleotides capable of conferring a desired phenotype are identified. Therapeutic, diagnostic and research methods and compositions employing such oligonucleotides are provided. Prior knowledge of the sequence or structure of a target molecule is generally not required.
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Ecker David J.
Mirabelli Christopher K.
Robertson Debra L.
Vickers Timothy A.
Chambers Jasemine C.
Isis Phamaceuticals, Inc.
Priebe Scott D.
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