Identification of new CD8 epitopes from HIV-1 proteins

Details Identification of new CD8 epitopes from HIV-1 proteins Identification of new CD8 epitopes from HIV-1 proteins

2006-01-26

2008-10-07

Campell, Bruce (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S184100, C424S185100, C424S186100, C424S187100, C424S193100, C530S300000, C435S005000, C435S007200, C435S007210, C435S007240

Reexamination Certificate

active

07431928

ABSTRACT:
The invention relates to the identification and the selection of CTL epitopes able to induce a protection against an HIV infection. More particularly, the invention is concerned with peptides and nucleic acid sequence coding for these peptides derived from HIV-1 proteins such as GAG, POL, ENV, VIF, TAT, VPU, REV and their applications. Preferably the immunogenic peptides are selected from the group consisting of SEQ ID NOs:1 to 18 and functional derivatives thereof. The invention also relates to antibodies directed against said peptides.

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