Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-02-15
1997-08-12
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 8, 435 32, 435 34, 4351723, 4352531, C12Q 170, C12Q 166, C12Q 118, C12N 120
Patent
active
056564244
ABSTRACT:
Methods for using reporter mycobacteriophage (RM) and p-nitro-.alpha.-acetylamino-.beta.-hydroxy-propiophenone (NAP) to identify TB complex mycobacteria and distinguish these species from MOTT. RM-infected MOTT show little or no reduction in signal when treated with NAP. In contrast, TB complex mycobacteria infected with RM are distinguishable from RM-infected MOTT by a reduction in signal with NAP treatment.
REFERENCES:
Laszlo, A. and Siddigi, S.H. 1984. Evaluation of a Rapid Radiometric Diffntiation Test for the Mycobacterium tuberculosis Complex by Selective Inhibition with p-Nitro-.alpha.-Acetyamine-.beta.-Hydroxypropiophenone, Journal of Clinical Microbiology, 1965), 694-698.
Bloom Barry R.
Chan John
Hamilton Paul T.
Jurgensen Stewart
Little Michael C.
Albert Einstein College of Medicine, a Division of Yeshiva Unive
Robinson Douglas W.
Wai Thanda
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