Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2006-04-25
2006-04-25
Ponnaluri, Padmashri (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S004000, C435S006120, C435S007100, C435S007200, C435S007310, C435S007320, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500
Reexamination Certificate
active
07033748
ABSTRACT:
The invention provides methods useful for identifying polynucleotides expressed in vivo by a microbe during infection of a host. Antibodies against antigens that are expressed by the microbe in vivo and in vitro are adsorbed with cells or cellular extracts of the microbe that have been grown in vitro. Unadsorbed antibodies are isolated and are probed against a phage display library of the microbe's DNA or RNA. A polynucleotide of the microbe that is expressed in vivo is isolated and identified.
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iviGene Corporation
McDonnell Boehnen & Hulbert & Berghoff LLP
Ponnaluri Padmashri
Shibuya Mark L.
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