Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-10-20
1999-06-15
Ulm, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 4352523, 4353201, 436501, G01N 3353
Patent
active
059121327
ABSTRACT:
The invention is directed to a method for identifying substances acting as ligands for transfected receptors by using transfected markers to measure receptor/ligand interactions.
REFERENCES:
patent: 5401629 (1995-03-01), Harpold et al.
Gutkind et al. "Muscarinic acetylcholine receptor subtypes as agonist-dependant oncogenes". P.N.A.S. 88:4703-4707, Jun. 1991.
Weyer et al. "Establishment of a Cellular Assay System for G Protein-Linked Receptors: Coupling of Human NK2 and 5-HT2 Receptors to Phospholipase C Activates a Luciferase Reporter Gene". Receptors and Channels 1:193-200, 1993.
Himmler et al. "Functional Testing of Human Dopamine D1 and D5 Receptors Expressed in Stable cAMP-Responsive Luciferase Reporter Cell Lines". J. of Receptor Res. 13(1-4):79-94, 1993.
Acadia Pharmaceuticals Inc.
Agris Cheryl H.
Ulm John
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