Identification of ligands by selective amplification of cells tr

Details Identification of ligands by selective amplification of cells tr Identification of ligands by selective amplification of cells tr

1997-11-07

1999-09-21

Ulm, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435455, C12N 1564

Patent

active

059552816

ABSTRACT:
The invention is directed to a method for identifying substances acting as ligands for transfected receptors by using transfected markers to measure receptor/ligand interactions.

REFERENCES:
patent: 5401629 (1995-03-01), Harpold et al.
Yamazaki et al. "A Deletion Mutation within the Ligand Binding Domain Is Responsible for Activation of Epidermal Growth Factor Receptor Gene in Human Brain Tumors". Jpn. J. Cencer Res. 81:773-779, Aug. 1990.
Hudson et al. "Identification and characterization of a regulated promoter element in the epidermal growth factor receptor gene". P.N.A.S. 87:7536-7540 Oct. 1990.

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