Identification of leucocytes bearing diagnostic markers for...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C436S501000, C436S536000, C436S513000, C436S547000

Reexamination Certificate

active

07601506

ABSTRACT:
The invention provides a simple method for diagnosing a non-symptomatic or symptomatic human or animal with transmissible spongiform encephalopathy.

REFERENCES:
patent: 7041807 (2006-05-01), Cashman et al.
patent: 2004/0072236 (2004-04-01), Cashman et al.
patent: 2005/0239139 (2005-10-01), Estey et al.
patent: 2008/0113387 (2008-05-01), Bujdoso
patent: 1 215 497 (2002-06-01), None
patent: WO 00/78344 (2000-12-01), None
patent: WO 03/073106 (2003-09-01), None
patent: WO2006/079805 (2006-03-01), None
Nouanthong et al (2006) Clinical and Vaccine Immunology. 13(5): 598-601.
Carmona et al (2005) Journal of General Virology. 86: 3425-3431.
Morel, et al., “Selective and efficient Immunoprecipitation of the Disease-associated form of the Prion Protein can be Mediated by Nonspecific Interactions between Monoclonal Antibodies and Scrapie-associated Fibrils”, The Journal of Biological Chemistry, vol. 279, No. 29, pp. 30143-30149 (2004).
Rhie, et al., “Characterization of 2′-Fluoro-RNA Aptamers that Bind Preferentially to Disease-associated Conformations of Prion Protein and Inhibit Conversion”, The Journal of Biological Chemistry, vol. 278, No. 41, pp. 39697-39705 (2003).
Sayer, et al., “Structural Determinants of Conformationally Selective, Prion-binding Aptamers”, The Journal of Biological Chemistry, vol. 279, No. 13, pp. 13102-13109 (2004).
Tayebi, et al., “Disease-Associated Prion Protein Elicits Immunoglobulin M Responses In Vivo”, Molecular Medicine, vol. 10, No. 7-12, p. 104-111 (2004).
Zou, et al., “Antibody to DNA detects scrapie but not normal prion protein”, PNAS, vol. 101, No. 5, p. 1380-1385 (2004).
Thackray, et al., “Conformational variation between allelic variants to cell-surface ovine prion protein”, Biochem. J., 381, p. 221-229 (2004).
Hunter, et al., “Transmission of prion diseases by blood transfusion”, Journal of General Virology, 83, p. 2897-2905 (2002).
Coulthart, et al., “Variant Creutzfeldt-Jakob disease: a summary of current scientific knowledge in relation to public health”, CMAJ, 165(1):51-58 (2001).
Cashman, “A prion primer”, Can Med. Assoc. J., 157(10:1381-1385 (1997).
Will, et al., “A new variant of Creutzfeldt-Jakob disease in the UK”, The Lancet, vol. 347, p. 921-925 (1996).
Collinge, “Variant Creutzfeldt-Jakob disease”, The Lancet, vol. 354, p. 317-323 (1999).
Paramithiotis, et al., “A prion protein epitope selective for the pathologically misfolded conformation”, nature Medicine, vol. 9, No. 7, pp. 893-899 (2003).
Schmerr, et al., “Use of capillary electrophoresis and fluorescent labeled peptides to detect the abnormal prion protein in the blood of animals that are infected with a transmissible spongiform encephalopathy”. Journal of Chromatography A, 853 p. 207-214 (1999).
Korth, et al., “Prion (PrPSC)-specific epitope defined by a monoclonal antibody”, Nature, vol. 390, p. 74-77 (1997).
Proske, et al., “Prion-Protein-Specific Aptamer Reduces PrPSCFormation”, ChemBioChem, 3, 717-725 (2002).
Sekiya, et al., “In vitro selection of RNA aptamers against cellular and abnormal isoform of mouse prion protein”, Nucleic Acids Symposium Series No. 49, 361-362 (2005).
Aguzzi, et al., “Progress and problems in the biology, diagnostics, and therapeutics of prion diseases”, The Journal of Clinical Investigation, vol. 114, No. 2, pp. 153-159(2004).
Schmerr, et al., “Use of capillary electrophoresis and fluorescent labeled peptides to detect the abnormal prion protein in the blood of animals that are infected with a transmissible spongiform encephalopathy”, Journal of Chromatography A, 853 (1999) 207-214.
Parish, et al., “Latex Bead Rosetting Method for Cell Surface Antigens”, Journal of Immunological Methods, 53 (1982) 367-372.
Ironside, et al., “Variant Creutzfeldt-Jakob disease and its transmission by blood”, Journal of Thrombosis and Haemostasis 1:1479-1486, (2006).
International Search Report for Corresponding PCT Application No. PCT/US2007/074454 dated Oct. 29, 2007.
Deleault, et al., “RNA molecules stimulate prion protein conversion”, Nature, vol. 425, pp. 717-720 (2003).
Weiss, et al., “RNA Aptamers Specifically Interact with the Prion Protein PrP”, Journal of Virology, vol. 71, No. 11, pp. 8790-8797 (1997).
Zanusso, et al., “Prion protein expression in different species: Analysis with a panel of new mAbs”, Proc. Natl. Acad. Sci. USA, vol. 95, pp. 8812-8816 (1998).
Féraudet, et al., “Screening of 145 Anti-PrP Monoclonal Antibodies for Their Capacity to Inhibit PrPSc Replication in Infected Cells”, The Journal of Biological Chemistry, vol. 280, No. 12, pp. 11247-11258 (2005).

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