Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1998-08-11
1999-10-26
Weddington, Kevin E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
424 9362, 424 9363, 514192, 514199, 514200, A61K 4900, A61K 3143
Patent
active
059723092
ABSTRACT:
Intra-erythrocytic exogenous bacterial structures or parasites seen by giemsa and phase contrast microscopy in several patients with systemic lupus erythematosus (SLE) and not in controls were identified as bacteria. Treatment of an SLE patient is contemplated with an antibacterial amount of a rifamycin in conjunction with an antibacterial amount of either a macrolide such as clarithromycin or a third generation cephalosporin such as cefpodoxime that is itself more preferably used in conjunction with an adjuvant amount of probenecid.
REFERENCES:
patent: 4329331 (1982-05-01), Kallick
patent: 5585243 (1996-12-01), Aster et al.
patent: 5811446 (1998-09-01), Thomas
Chemical Abstracts (92:208753) 1979.
Lahita, R. G., Systemic Lupus Erythematosus, Churchill, Livingston, New York, p. XXIX (1987).
Taurog, et al., Intern J. Derm., 20:149-158 (1981).
Crow, et al., "Etiologic Hypothesis for Systemic Lupud Erythematosus", Lahita, Systemic Lupus Erythematosus, Churchill, Livingston, New York, p. 54 (1987).
Pincus, Arthr & Rheum, 20:149-158 (1982).
Kallick, et al., Nature New Biology, 236:145-146 (1972).
Kallick, et al, Arthr & Rheum, 23:197-205 (1980).
Miller, et al., eds., Immunity to Blood Parasites in Animals and Man, Plenum Press, New York, pp. 155-188 (1977).
Franklin, et al., Southwestern Vet., 15:131-139 (1962).
Brown, et al., J. Lab. Clin. Med., 34:1404-1410 (1949).
Scheff, et al., Infec. Dis., 98:113 (1956).
Ristic, et al., J. Vet. Res., 19:37 (1958).
Dubois, Lupus Erythematosus, 2d ed., U.S. California Press, Los Angeles (1974).
Krier, Ann. Rev. Microbiol., 325-338 (1981).
Coon, so. Amer. J. Surgery, 155:391 (1988).
Goodman and Gilman's The Pharmaceutical Basis of Therapeutics, 8th ed., McGraw-Hill, Inc., New York, pp. 1085-1092 (1993).
Gennaro, et al., eds., Remington's Pharmaceutical Sciences, 18th ed., Mack Publishing Co., Easton, PA, pp. 1193-1200 (1990).
Physician's Desk Reference, PDR.RTM., 48th ed., Medical Economics Data Production Co., Montavale, NJ, Product Category Index, pp. 203-204, and individual listings (1994).
The Merck Index, 11th ed., Merck & Co., Rahway, NJ, (1989) individual listings.
Morrison, et al., J. Clin. Microbiol., 24(5):835-855 (1986).
LandOfFree
Identification of an exogenous intra-erythrocytic bacterium in p does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Identification of an exogenous intra-erythrocytic bacterium in p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Identification of an exogenous intra-erythrocytic bacterium in p will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-760522