Identification and use of selective inhibitors of glycogen synth

Details Identification and use of selective inhibitors of glycogen synth Identification and use of selective inhibitors of glycogen synth

1997-04-02

2000-05-02

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

514 2, 514 3, 435194, 530300, 530350, A61K 3100

Patent

active

060572868

ABSTRACT:
The invention provides for use of selective inhibitors of GSK3 for treatment of diseases that are mediated by GSK3 activity, including non-insulin dependent diabetes mellitus (NIDDM) and Alzheimer's disease. Also described are methods of identifying inhibitors of GSK3 activity. The selective GSK3 inhibitor can be a peptide, peptoid, small organic molecule, or polynucleotide.

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