Identification and preparation of epitopes on antigens and aller

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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436543, 514 17, 514 16, 514 15, 514 14, 514 13, 514 12, 514 2, 424 88, C07C10352, C07G 700, G01N 3354, A61K 3700

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045541019

ABSTRACT:
An immunoglobulin is provided which consists essentially of a mono-specific, hetero-molecular antibody which is mono-specific to a single antigenic or allergenic determinant. The antibody is specific to the H-epitope of a protein antigen or allergen. The H-epitope is defined by a sequence of at least six amino acids corresponding to the sequence of such amino acids in the protein antigen or allergen where the greatest local average hydrophilicity of the protein antigen or allergen is found.

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