Identification and molecular cloning of a gene encoding a fibron

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 6, 536 231, 536 243, 536 2431, 536 2432, 536 2433, C12P 1934, C12Q 168, C07H 2104

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061565466

ABSTRACT:
A novel gene encoding a 37 kDa outer membrane protein from Campylobacter coli M275 has been cloned and sequenced. This protein has been named CadF and is expressed in a large number of clinical isolates of Campylobacter species. The invention also provides assays for detecting the presence of pathogenic Campylobacter species based on the antibody-based detection of CadF, or the polymerase chain reaction (PCR)-based amplification of a segment of the C. coli cadF gene.

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