Identification and isolation of novel polypeptides having WW dom

Details Identification and isolation of novel polypeptides having WW dom Identification and isolation of novel polypeptides having WW dom

1996-04-03

2000-01-04

Eyler, Yvonne

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530350, 435810, 435975, 435 697, 435 71, A61K 3800, C07K 100, G01N 3353, C12P 2104

Patent

active

060111372

ABSTRACT:
Novel polypeptides having WW domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.

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