Idene analogs of mevalonolactone and derivatives thereof

Details Idene analogs of mevalonolactone and derivatives thereof Idene analogs of mevalonolactone and derivatives thereof

1988-07-01

1991-03-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 53, 556441, 549264, 549291, 562462, 562466, C07C 6976

Patent

active

050012550

ABSTRACT:
Compounds of the formula ##STR1## the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

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