Ibuprofen p-hydroxyphenylurea ester

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters


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424308, C07C12719




Ibuprofen p-hydroxyphenylurea ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [.+-.2-(p-isobutylphenyl)propionic acid](I).
The ester II above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis.

patent: 3931285 (1976-01-01), Morozowich


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