Ibuprofen p-hydroxybenzaldehyde semicarbazone ester

Details Ibuprofen p-hydroxybenzaldehyde semicarbazone ester Ibuprofen p-hydroxybenzaldehyde semicarbazone ester

1976-06-17

1977-09-20

Myers, Jane S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

424308, C07C13308

Patent

active

040496996

ABSTRACT:
Ibuprofen p-hydroxybenzaldehyde semicarbazone ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [.+-.2-(p-isobutylphenyl)propionic acid] (I).
The ester II above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis.

REFERENCES:
patent: 3931285 (1976-01-01), Morozowich

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