Ibuprofen-containing soft gelatin capsules and process for prepa

Details Ibuprofen-containing soft gelatin capsules and process for prepa Ibuprofen-containing soft gelatin capsules and process for prepa

1985-03-08

1987-09-01

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424455, 514570, 514789, 514960, 514962, A61K 3119, A61K 948

Patent

active

046908234

ABSTRACT:
Soft gelatin capsules containing a solution of from 15 to 30 parts by weight of ibuprofen in from 70 to 85 parts by weight of polyoxyethylene-polyoxypropylene polymer or in a mixture of from 30 to 76 parts by weight of polyalkylene glycol and from 7 to 40 parts by weight of a surfactant have a very rapid and high bio-availability of the active ingredient. The active ingredient is not re-precipitated therefrom by aqueous media such as artificial gastric juice.

REFERENCES:
patent: 4145440 (1979-03-01), Fitch et al.
patent: 4278633 (1981-07-01), Fujii
patent: 4361580 (1982-11-01), Peck et al.
patent: 4428927 (1984-01-01), Ebert et al.
patent: 4473584 (1984-09-01), Heckler
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4555524 (1985-11-01), Gruber et al.

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