I- Cre I meganuclease variants with modified specificity,...

Details I- Cre I meganuclease variants with modified specificity,... I- Cre I meganuclease variants with modified specificity,...

2011-03-01

2011-03-01

Fronda, Christian L (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S183000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07897372

ABSTRACT:
Method of preparing 1-CreI meganuclease variants having a modified cleavage specificity, variants obtainable by said method and their applications either for cleaving new DNA target or for genetic engineering and genome engineering for non-therapeutic purposes. Nucleic acids encoding said variants, expression cassettes comprising said nucleic acids, vectors comprising said expression cassettes, cells or organisms, plants or animals except humans, transformed by said vectors.

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