Hypotonic compositions for selectively killing undesirable lens

Details Hypotonic compositions for selectively killing undesirable lens Hypotonic compositions for selectively killing undesirable lens

1989-05-18

1991-10-29

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514912, A61K 31715

Patent

active

050616960

ABSTRACT:
A hypotonic composition for selectively destroying lens cells in humans and other mammals such as lens epithelial cells that would otherwise cause clouding of the lens capsule after removal of the lens from the capsule includes one or more ocularly biocompatible viscoelastic substances that have the capacity for destroying such cells osmotically in small concentrations in hypotonic aqueous solutions, yet are sufficiently viscoelastic to attack only tissues to which they are applied without leaking or otherwise flowing onto the damaging adjacent and neighboring tissue. Such compositions are placed intraocularly in the lens capsule by applying a sufficient quantity of the composition to the epithelial cells to be destroyed to destroy them without damaging or otherwise destroying neighboring eye tissue.

REFERENCES:
patent: 4486416 (1984-12-01), Stoll et al.

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