Hypotensive imidazole-5-acetic acid derivatives

Details Hypotensive imidazole-5-acetic acid derivatives Hypotensive imidazole-5-acetic acid derivatives

1980-11-05

1982-10-19

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548336, 548337, 548342, A61K 31415, C07D23368

Patent

active

043550401

ABSTRACT:
Novel imidazole-5-acetic acid derivatives of the formula: ##STR1## wherein R.sup.1 is lower alkyl, cycloalkyl or, phenyl which may be substituted with one to three of halogen, nitro, amino, mono(lower alkyl)amino, di(lower alkyl)amino, lower alkyl, lower alkoxyl, benzyloxyl or/and hydroxyl; X.sup.1, X.sup.2 and X.sup.3 are each hydrogen, halogen, nitro, amino, lower alkyl, lower alkoxyl, benzyloxyl or hydroxyl; Y is halogen and R.sup.2 is hydrogen or lower alkyl; provided that X.sup.1 is halogen, lower alkyl, lower alkoxyl, benzyloxyl or hydroxyl when R.sup.1 is unsubstituted or substituted phenyl only with one halogen, di(lower alkyl)amino, lower alkyl or lower alkoxyl, and its salts have hypotensive activity.

REFERENCES:
patent: 4207324 (1980-06-01), Matsumura et al.
Karppanen, Agents and Actions 9:84-85 (1979).
Maxwell, M. (Editor), Advances in Nephrology, 8, 297-319 (1979).

Affiliated with

Also associated with

Rating

Hypotensive imidazole-5-acetic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hypotensive imidazole-5-acetic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hypotensive imidazole-5-acetic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1338544