Hypotensive ajmalicine derivatives

Details Hypotensive ajmalicine derivatives Hypotensive ajmalicine derivatives

1978-02-24

1979-11-06

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 41, A61K 31445, C07D49122

Patent

active

041736354

ABSTRACT:
The invention relates to new derivatives of ajmalicine of the formula: ##STR1## in which R represents either a hydrogen atom or a linear or branched alkyl radical having 1 to 6 carbon atoms and which may be substituted with at least one hydroxy group.
These derivatives may be prepared by reacting hydrazine or a hydrazine hydrate with ajmalicine.
These compounds may be used as hypotensive drugs.

REFERENCES:
patent: 2046432 (1936-07-01), Senn
March, J., Advanced Organic Chemistry, McGraw-Hill, New York, 1968, pp. 589-590.

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